Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Shh  sonic hedgehog   (Synonyms: Hhg1)
Results	Reference
1	J:178985 Alvarez JI, Dodelet-Devillers A, Kebir H, Ifergan I, Fabre PJ, Terouz S, Sabbagh M, Wosik K, Bourbonniere L, Bernard M, van Horssen J, de Vries HE, Charron F, Prat A, The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science. 2011 Dec 23;334(6063):1727-31
1	J:277407 Barez-Lopez S, Obregon MJ, Bernal J, Guadano-Ferraz A, Thyroid Hormone Economy in the Perinatal Mouse Brain: Implications for Cerebral Cortex Development. Cereb Cortex. 2018 May 1;28(5):1783-1793
1	J:150524 Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA, Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nat Neurosci. 2009 Apr;12(4):409-17
1	J:155992 Ching S, Vilain E, Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia. Genesis. 2009 Sep;47(9):628-37
1	J:227188 Choe Y, Huynh T, Pleasure SJ, Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets. Elife. 2015;4
1	J:244957 El Shahawy M, Reibring CG, Neben CL, Hallberg K, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A, Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. PLoS Genet. 2017 Jul;13(7):e1006914
1	J:173840 El-Hashash AH, Al Alam D, Turcatel G, Rogers O, Li X, Bellusci S, Warburton D, Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol. 2011 May 15;353(2):242-58
1	J:154650 Favaro R, Valotta M, Ferri AL, Latorre E, Mariani J, Giachino C, Lancini C, Tosetti V, Ottolenghi S, Taylor V, Nicolis SK, Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh. Nat Neurosci. 2009 Oct;12(10):1248-56
1	J:321427 Fons Romero JM, Star H, Lav R, Watkins S, Harrison M, Hovorakova M, Headon D, Tucker AS, The Impact of the Eda Pathway on Tooth Root Development. J Dent Res. 2017 Oct;96(11):1290-1297
1	J:80081 Gritli-Linde A, Bei M, Maas R, Zhang XM, Linde A, McMahon AP, Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization. Development. 2002 Dec;129(23):5323-37
1	J:117334 Gritli-Linde A, Hallberg K, Harfe BD, Reyahi A, Kannius-Janson M, Nilsson J, Cobourne MT, Sharpe PT, McMahon AP, Linde A, Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell. 2007 Jan;12(1):99-112
1	J:71184 Gritli-Linde A, Lewis P, McMahon AP, Linde A, The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides. Dev Biol. 2001 Aug 15;236(2):364-86
1*	J:38389 Jensen AM, Wallace VA, Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina. Development. 1997 Jan;124(2):363-71
1*	J:252112 Kim JJ, Jiwani T, Erwood S, Loree J, Rosenblum ND, Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15. Dev Dyn. 2018 Jan;247(1):156-169
1	J:32723 Koyama E, Yamaai T, Iseki S, Ohuchi H, Nohno T, Yoshioka H, Hayashi Y, Leatherman JL, Golden EB, Noji S, Pacifici M, Polarizing activity, Sonic hedgehog, and tooth development in embryonic and postnatal mouse. Dev Dyn. 1996 May;206(1):59-72
1	J:191495 Kucerova R, Dora N, Mort RL, Wallace K, Leiper LJ, Lowes C, Neves C, Walczysko P, Bruce F, Fowler PA, Rajnicek AM, McCaig CD, Zhao M, West JD, Collinson JM, Interaction between hedgehog signalling and PAX6 dosage mediates maintenance and regeneration of the corneal epithelium. Mol Vis. 2012;18:139-50
1	J:92189 Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP, Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Dev Biol. 2004 Jun 15;270(2):393-410
1	J:202355 Liu HX, Ermilov A, Grachtchouk M, Li L, Gumucio DL, Dlugosz AA, Mistretta CM, Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance. Dev Biol. 2013 Oct 1;382(1):82-97
1	J:85603 Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, Corbin JG, Gritli-Linde A, Dellovade T, Porter JA, Rubin LL, Dudek H, McMahon AP, Fishell G, Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron. 2003 Sep 11;39(6):937-50
1*	J:73657 Miller LA, Wert SE, Whitsett JA, Immunolocalization of sonic hedgehog (Shh) in developing mouse lung. J Histochem Cytochem. 2001 Dec;49(12):1593-604
1	J:139012 Mohri Y, Kato S, Umezawa A, Okuyama R, Nishimori K, Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4. Dev Dyn. 2008 Aug;237(8):2235-42
1	J:207286 Nowak JA, Polak L, Pasolli HA, Fuchs E, Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell. 2008 Jul 3;3(1):33-43
1*	J:64180 Outram SV, Varas A, Pepicelli CV, Crompton T, Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte. Immunity. 2000 Aug;13(2):187-97
1	J:137825 Passman JN, Dong XR, Wu SP, Maguire CT, Hogan KA, Bautch VL, Majesky MW, A sonic hedgehog signaling domain in the arterial adventitia supports resident Sca1+ smooth muscle progenitor cells. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9349-54
1	J:234178 Perdigoto CN, Dauber KL, Bar C, Tsai PC, Valdes VJ, Cohen I, Santoriello FJ, Zhao D, Zheng D, Hsu YC, Ezhkova E, Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet. 2016 Jul;12(7):e1006151
1	J:54642 Podlasek CA, Barnett DH, Clemens JQ, Bak PM, Bushman W, Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium. Dev Biol. 1999 May 1;209(1):28-39
1	J:185828 Ren Y, Cowan RG, Migone FF, Quirk SM, Overactivation of hedgehog signaling alters development of the ovarian vasculature in mice. Biol Reprod. 2012 Jun;86(6):174
1*	J:135151 Sigulinsky CL, Green ES, Clark AM, Levine EM, Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina. Dev Biol. 2008 May 15;317(2):560-75
1	J:195123 Takeda N, Jain R, Leboeuf MR, Padmanabhan A, Wang Q, Li L, Lu MM, Millar SE, Epstein JA, Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells. Development. 2013 Apr;140(8):1655-64
1	J:238248 Wang L, Hou S, Han YG, Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016 Jul;19(7):888-96
1	J:82377 Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA, Baylin SB, Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature. 2003 Mar 20;422(6929):313-7
1	J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26
1*	J:332246 Xie F, Zhu X, Liu X, Chen H, Wang J, N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis. J Biol Chem. 2022 Dec;298(12):102715
1	J:306911 Yamashiro K, Hori K, Lai ESK, Aoki R, Shimaoka K, Arimura N, Egusa SF, Sakamoto A, Abe M, Sakimura K, Watanabe T, Uesaka N, Kano M, Hoshino M, AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication. iScience. 2020 Dec 18;23(12):101820
1	J:93296 Yu H, Wessels A, Chen J, Phelps AL, Oatis J, Tint GS, Patel SB, Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome. BMC Dev Biol. 2004 Mar 2;4(1):1
1	J:173529 Yu T, Yaguchi Y, Echevarria D, Martinez S, Basson MA, Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum. Development. 2011 Jul;138(14):2957-68
1	J:150793 Zhou S, Degan S, Potts EN, Foster WM, Sunday ME, NPAS3 is a trachealess homolog critical for lung development and homeostasis. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11691-6